Radar Prostate Cancer Zoledronic Acid

Published on May 27 2010, in the categories: Related topics

The zoledronic acid or zoledronate is a bisphosphonate, marketed by Novartis under the trade names of Zomera, Aclasta, Zometa and Reclast and it is recommended for preventing skeletal fractures in patients with bone metastases, cause mainly by diseases such as the prostate cancer and multiple myeloma. The effects of zoledronic acid on prostate cancer are still under study but the certain fact is that this compound can treat osteoporosis and is processed via the kidneys, so it is contraindicated for pregnancy, hipocalcemia, paralysis and poor renal function.

Cancer is seen as an abnormal condition having as main causes the factors mentioned before which allow the multiplication and fast development of the cancer cells and malignant tumors and prevent the well functioning of the apoptotic reaction and the mitosis; each cancer is unique and that means that the same type of cancer can have different characteristics reported in different patients.

In America only the lung cancer is to be blamed for the numerous reported deaths followed immediately by the prostate cancer.

radar-prostate-cancer-zoledronic-acid

The prognosis for the outcome of the prostate cancer is rather pessimistic and several research studies have shown that despite the treatment discoveries announced almost every year, the prostate cancer still remains the most common type of cancer which affects the male population from all around the world, with one in six men diagnosed with a prostate cancer.

Several factors are to be held responsible for allowing the apparition and progression of a prostate cancer such as age, the working environment, the foods one consumes after a certain age, race and genetic inheritance, etc.

In different people the cancer can progress at different stages in different periods of time with different consequences and treatment effects; this whole thing makes the prognosis rather difficult and relative.

The results of the screening tests are interpreted by doctors because they don’t offer an accurate result whether cancer exists or not; with the digital rectal exam the physician can only palpate de size of the prostate and sense any abnormality with it and the prostate specific antigen blood tests can only indicate the level of the prostate specific antigen protein, which should be low in normal conditions.

The prostate biopsy, complemented by the nomogram or the prostate mapping, is the best method of detection and can give an accurate diagnose.

radar-prostate-cancer-zoledronic-acid

The grading is also done with the Gleason scale, which is not the only available system but it is certainly the most popular one. This whole activity of grading and staging is done only if cancer is diagnosed with the help of the screening tests or the prostate biopsy.

The stages of the cancer can be determined with the available staging systems such as the Whitmore-Jewett system or the TNM or tumor, nodes and metastatic system.

The patient can respond well to a correct prescribed treatment and the fortunate fact is that if the cancer is detected early those treatments can prevent or even stop the progression of cancer, mostly because of its slow growth, in general the tumor doubling its size once every four years. Those treatments can be complemented with the use of strong drugs or other medical or mineral supplements.

The spreading process is done through the lymph system and vessels and bloodstream and can take several years for the tumor to reach outside the prostate capsule and reach the surrounding areas such as the liver and the bladder, becoming locally advanced, or infecting far distance regions of the body such as the bone system and affecting vital organs such as the lungs and brain: this is the stage of metastatic cancer.

radar-prostate-cancer-zoledronic-acid-2

Bone metastases caused by the prostate cancer can be treated with the zoledronic acid in certain recommended quantities or doses.

The standard dose of zoledornic acid for prostate cancer patients is four mg infused intravenously every three or four weeks.

The signs and symptoms of the zoledronic acid in prostate cancer are fever, anemia, muscle aches, fatigue, swelling in the legs, flu-like symptoms, etc.
If you liked this post, subscribe to our blog by filling your e-mail address below:
Delivered by FeedBurner

Want to add something? Post your comments